New depression pill shows promise in early trial

NCT ID NCT06126497

Completed Symptom relief Sponsor: Suven Life Sciences Limited Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new drug called ropanicant in 41 adults with moderate to severe major depressive disorder. The main goal was to check safety and side effects, while also measuring how well it improved depression symptoms using a standard rating scale. The trial was open-label, meaning everyone knew they were getting the drug, and it has already been completed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ropanicant (also known as SUVN-911)
What this could lead to: If successful, this could point toward a new treatment option for people with moderate to severe depression.
What could go wrong: This was a small, early-phase trial (41 people) with no placebo group, so results may not be reliable or generalizable. Side effects are possible and long-term benefits are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depression major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER

Contacts and locations

Locations

Cedar Clinical Research, Inc.

Murray, Utah, 84107, United States
CenExel iResearch, LLC

Decatur, Georgia, 30030, United States
CenExel iResearch, LLC

Savannah, Georgia, 31405, United States
Clinical Innovations, Inc

Bellflower, California, 90706, United States
Collaborative Neuroscience Research, LLC

Torrance, California, 90504, United States
Eastside Therapeutic Resource, Inc. dba Core Clinical Research

Everett, Washington, 98201, United States
Innovative Clinical Research, Inc.

Miami Lakes, Florida, 33016, United States
NRC Research Institute

Orange, California, 92868, United States
Neuro behavioral Clinical Research, Inc

North Canton, Ohio, 44720, United States
Precise Research Centers

Flowood, Mississippi, 39232, United States

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