Pill vs. needle: can a simple tablet prevent dangerous clots after leg injuries?
NCT ID NCT06195540
First seen Jan 04, 2026 · Last updated May 15, 2026 · Updated 21 times
Summary
This study compares two blood thinners—rivaroxaban (a pill) and low-molecular-weight heparin (a daily injection)—in people with leg injuries that require a cast or brace for at least two weeks. The goal is to see if the pill is as good as or better than the injection at preventing blood clots in the legs or lungs. About 1,424 high-risk participants will be followed for 90 days to check for clots, bleeding, and treatment satisfaction.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Agen-Nerac Hospital, Emergency Department
NOT_YET_RECRUITINGAgen, 47923, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Angers University Hospital, Emergency department
RECRUITINGAngers, 49000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Argenteuil hospital, Emergency department
RECRUITINGArgenteuil, 95100, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Arpajon Hospital, Emergency Department
NOT_YET_RECRUITINGArpajon, 91294, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Bichat Hospital, Adult Emergency department
RECRUITINGParis, 75018, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Caen University hospital, Emergency department
WITHDRAWNCaen, 14000, France
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Cholet Hospital, Emergency department
RECRUITINGCholet, 49300, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Clermont-Ferrand University Hospital, Emergency department
RECRUITINGClermont-Ferrand, 63000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cochin Hospital, Emergency department
RECRUITINGParis, 75014, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Edouard Herriot University Hospital, Emergency Department
RECRUITINGLyon, 69000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Eure-Seine Hospital, Emergency Departement
RECRUITINGÉvreux, 27015, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Grenoble University Hospital, Emergency Department
RECRUITINGGrenoble, 38000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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HEGP, Emergency Department
RECRUITINGParis, 75015, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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La Pitié-Salpétrière Hospital, Emergency Department
NOT_YET_RECRUITINGParis, 75013, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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La Rochelle Hospital, Adult emergency departement
RECRUITINGLa Rochelle, 17000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Lariboisière hospital, emergency department
NOT_YET_RECRUITINGParis, 75010, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Le Mans Hospital, Emergency department
RECRUITINGLe Mans, 72000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Limoges University hospital, Emergency department
RECRUITINGLimoges, 87000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Marseille University Hospital, Emergency department
RECRUITINGMarseille, 13005, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Melun Hospital, Emergency Department
NOT_YET_RECRUITINGMelun, 77000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Montpellier University Hospital, emergency department
RECRUITINGMontpellier, 34000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nantes University Hospital, Emergency department
RECRUITINGNantes, 44000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nice University Hospital, Emergency department
WITHDRAWNNice, 06000, France
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Niort Hospital, Emergency Department
RECRUITINGNiort, 79000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Poitiers University Hospital, Emergency department
RECRUITINGPoitiers, 86000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Rennes University Hospital, Emergency department
RECRUITINGRennes, 35000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Rouen University Hospital, Emergency Department
NOT_YET_RECRUITINGRouen, 76000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Saint-Antoine Hospital, Emergency department
RECRUITINGParis, 75012, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Simone Veil Hospital, Emergency Department
RECRUITINGEaubonne, 95600, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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South Lyon University Hospital, Emergency department
RECRUITINGPierre-Bénite, 69495, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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St-Joseph Hospital, Emergency Department
RECRUITINGParis, 75014, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Strasbourg University Hospital, Emergency Department
RECRUITINGStrasbourg, 67000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Toulouse University Hospital, Emergency Department
RECRUITINGToulouse, 31000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tours University Hospital, Emergency department
WITHDRAWNChambray-lès-Tours, 37170, France
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Vannes Hospital, Emergency Department
NOT_YET_RECRUITINGVannes, 56000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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