New nerve block may cut opioid use after gallbladder surgery

NCT ID NCT06768593

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested whether an ultrasound-guided nerve block called RIFP can reduce pain and the need for rescue painkillers after laparoscopic gallbladder removal. 77 patients were enrolled. The block targets nerves in the upper abdomen to provide pain relief. The main goal was to see if it lowers opioid use in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

RIFP block (a nerve block using local anesthetic)

What this could lead to

If effective, this nerve block could become a standard way to manage pain after gallbladder surgery, reducing the need for strong painkillers.

What could go wrong

This is a small, completed trial with no phase designation, so results may not apply to all patients. The block may not significantly reduce pain or opioid use compared to standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Acute Pain agnosia Bites and Stings

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Istanbul Medipol University Mega Hospital Complex

    Istanbul, Bagcilar, 34212, Turkey (Türkiye)