New nerve block may cut opioid use after gallbladder surgery

NCT ID NCT06768593

Completed Symptom relief Sponsor: Istanbul Medipol University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested whether an ultrasound-guided nerve block called RIFP can reduce pain and the need for rescue painkillers after laparoscopic gallbladder removal. 77 patients were enrolled. The block targets nerves in the upper abdomen to provide pain relief. The main goal was to see if it lowers opioid use in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: RIFP block (a nerve block using local anesthetic)
What this could lead to: If effective, this nerve block could become a standard way to manage pain after gallbladder surgery, reducing the need for strong painkillers.
What could go wrong: This is a small, completed trial with no phase designation, so results may not apply to all patients. The block may not significantly reduce pain or opioid use compared to standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Acute Pain agnosia Bites and Stings

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE PAIN LAPAROSCOPIC CHOLECYSTECTOMY PAIN MANAGEMENT PLANE BLOCK

Contacts and locations

Locations

Istanbul Medipol University Mega Hospital Complex

Istanbul, Bagcilar, 34212, Turkey (Türkiye)

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