Can a gut pill tame Chemo's stomach troubles?

NCT ID NCT04249622

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 23 times

Summary

This study tested whether rifaximin, a medicine for gut issues, could reduce stomach pain, bloating, and diarrhea caused by pertuzumab-based chemotherapy in people with early-stage HER2-positive breast cancer. The goal was to help patients complete their cancer treatment without delays or dose reductions. The trial was stopped early, so results are limited.

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Contacts and locations

Locations

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224-9980, United States

Conditions

Explore the condition pages connected to this study.