Radiation zaps prostate cancer spots in men not helped enough by hormone drugs

NCT ID NCT07644754

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving radiotherapy to the prostate and to cancer spots seen on PET scans can help men with metastatic prostate cancer whose PSA levels remain high after six months of hormone therapy. Participants continue their hormone treatment and receive three PSMA-PET scans along with targeted radiation. The main goal is to see if the cancer stops growing on imaging one year after radiotherapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Radiotherapy
What this could lead to
If successful, this approach could offer a way to better control metastatic prostate cancer by targeting both the primary tumor and remaining cancer spots with radiation.
What could go wrong
This is a small, early-phase study with only 27 participants, so results may not apply to all patients. Radiotherapy can cause side effects like fatigue or local irritation, and the cancer may still progress.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

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