Warm-Up for kidneys: could a machine bath boost transplant success?

NCT ID NCT05782543

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether giving a donor kidney a 4-6 hour warm bath on a machine (normothermic machine perfusion) right before transplant helps it work better a year later. The trial includes 240 adults receiving a kidney from a donor aged 50 or older. Half get the standard cold storage, half get the extra warm perfusion.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Normothermic machine perfusion (a procedure that warms and pumps the kidney before transplant)

What this could lead to

If it works, this could improve kidney function after transplant and reduce complications like delayed graft function.

What could go wrong

This is a mid-stage trial with 240 participants, so results may not apply to all patients. The procedure adds time and complexity, and benefits are not guaranteed.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Erasmus Medical Center

    RECRUITING

    Rotterdam, Netherlands

    Contact Phone: •••-•••-••••

  • Leiden University Medical Center

    NOT_YET_RECRUITING

    Leiden, Netherlands

    Contact Phone: •••-•••-••••

  • University Medical Center Groningen

    RECRUITING

    Groningen, Provincie Groningen, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••