Warm-Up for kidneys: could a machine bath boost transplant success?

NCT ID NCT05782543

Recruiting now Disease control Sponsor: University Medical Center Groningen Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether giving a donor kidney a 4-6 hour warm bath on a machine (normothermic machine perfusion) right before transplant helps it work better a year later. The trial includes 240 adults receiving a kidney from a donor aged 50 or older. Half get the standard cold storage, half get the extra warm perfusion.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Normothermic machine perfusion (a procedure that warms and pumps the kidney before transplant)
What this could lead to: If it works, this could improve kidney function after transplant and reduce complications like delayed graft function.
What could go wrong: This is a mid-stage trial with 240 participants, so results may not apply to all patients. The procedure adds time and complexity, and benefits are not guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KIDNEY TRANSPLANT; COMPLICATIONS

Contacts and locations

Locations

Erasmus Medical Center
RECRUITING

Rotterdam, Netherlands
Leiden University Medical Center
NOT_YET_RECRUITING

Leiden, Netherlands
University Medical Center Groningen
RECRUITING

Groningen, Provincie Groningen, Netherlands

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