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Can a vaccine shield transplant patients from shingles?

NCT ID NCT05604911

Ongoing Knowledge-focused Sponsor: Susanne Dam Nielsen, MD, DMSc Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study looks at how the immune system of kidney transplant patients responds to the shingles vaccine and to natural shingles infection. Researchers will track antibody and T-cell levels over time in patients who have had a transplant or are on the waiting list. The goal is to understand these immune responses better, which could lead to improved ways to prevent and treat shingles in this vulnerable group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Shingrix® (recombinant varicella-zoster virus vaccine)
What this could lead to
If successful, this could lead to better vaccination strategies and improved prevention of shingles in kidney transplant patients.
What could go wrong
This is an observational study, so it won't directly test new treatments. Results may not lead to immediate changes in clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chickenpox end stage renal failure Vaccine-Preventable Diseases varicella zoster infection Varicella Zoster Virus Infection herpes zoster prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KIDNEY TRANSPLANT; COMPLICATIONS VACCINE-PREVENTABLE DISEASES VARICELLA ZOSTER VIRUS INFECTION

Contacts and locations

Locations

  • Department of Health Technology, Technical University of Denmark

    Lyngby, 2800, Denmark

  • Department of Infectious Diseases, Copenhagen University Hospital - Rigshospitalet

    Copenhagen, 2100, Denmark

  • Department of Nephrology, Aarhus University Hospital

    Aarhus, Denmark

  • Department of Nephrology, Copehagen University Hospital - Rigshospitalet

    Copenhagen, 2100, Denmark

  • Department of Nephrology, Odense University Hospital

    Odense, Denmark

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