Could a single infusion of 'Peacekeeper' cells let kidney transplant patients ditch most of their meds?

NCT ID NCT06552169

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether a single infusion of a patient's own regulatory T cells (TRK-001) can prevent the immune system from attacking a new kidney. 34 living-donor kidney transplant recipients will either receive standard anti-rejection drugs alone or those drugs plus the cell infusion. The goal is to see if the cell therapy allows patients to safely reduce to just one anti-rejection medication a year after transplant, while avoiding rejection and other complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

regulatory T cells (TRK-001) plus standard immunosuppression drugs

What this could lead to

If successful, this could allow kidney transplant recipients to safely reduce their lifelong anti-rejection medications to just one drug, lowering side effects and improving quality of life.

What could go wrong

This is a small, early-phase trial (34 people) testing safety and feasibility. The cell therapy may not work as hoped, and reducing immunosuppression could increase rejection risk. Long-term benefits are uncertain.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure transplant rejection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chang Gung Medical Foundation Hospital

    RECRUITING

    Taoyuan, 333, Taiwan

    Contact

  • Mayo Clinic in Arizona

    RECRUITING

    Phoenix, Arizona, 85054, United States

    Contact

  • Mayo Clinic in Minnesota

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact

  • National Cheng Kung University Hospital

    NOT_YET_RECRUITING

    Tainan, 704, Taiwan

    Contact

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 100229, Taiwan

    Contact

  • Northwestern Memorial Hospital

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact

  • Taichung Veterans General Hospital

    RECRUITING

    Taichung, 407219, Taiwan

    Contact