New drug could prevent repeat knee infections after surgery

NCT ID NCT07214311

Recruiting now Disease control Sponsor: Peptilogics Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 29 times

Summary

This study tests if a new drug called PLG0206 can stop infections from coming back in people who have had a knee replacement and need surgery to treat an infection. About 240 adults will get either PLG0206 or a placebo during their surgery, along with standard care. Researchers will track them for a year to see if the drug helps prevent the infection from returning.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Clinical Trial Site
RECRUITING

Sarasota, Florida, 34239, United States
Clinical Trial Site
RECRUITING

Tamarac, Florida, 33321, United States
Clinical Trial Site
RECRUITING

Baltimore, Maryland, 21215, United States
Clinical Trial Site
RECRUITING

Boston, Massachusetts, 02120, United States
Clinical Trial Site
RECRUITING

Cincinnati, Ohio, 45267, United States
Clinical Trial Site
RECRUITING

Columbus, Ohio, 43210, United States
Clinical Trial Site
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
Clinical Trial Site
RECRUITING

Edinburg, Texas, 78539, United States
Clinical Trial Site
RECRUITING

Morgantown, West Virginia, 26506, United States

Conditions

Explore the condition pages connected to this study.

PROSTHETIC JOINT INFECTION