Estudio exploratorio del potencial del ejercicio terapeútico en el tratamiento de la enfermedad de Willis-Ekbom

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥18 years. * Resident in Spain, preferably in or near the Community of Madrid. * Clinical diagnosis of restless legs syndrome (RLS) according to the 2014 International Restless Legs Syndrome Study Group (IRLSSG) diagnostic criteria, confirmed through clinical assessment by a neurologist. * Symptoms predominantly affecting the legs. * Under medical follow-up for at least 3 months before enrollment, regardless of current treatment or response to medication. * If receiving pharmacological treatment for RLS, treatment must have remained stable for at least 1 month before enrollment and must remain stable throughout the study. Exclusion Criteria: * Acute or chronic musculoskeletal conditions, such as symptomatic disc herniation, radiculopathy, severe tendinopathy, recent muscle injury, or advanced osteoarthritis, that limit or contraindicate prolonged stretching exercises. * Severe uncontrolled pain in the lumbar region, pelvis, or lower extremities that prevents completion of the stretching positions required by the protocol. * Initiation, concurrently with this study, of another non-pharmacological therapy for RLS, such as vibration or compression devices, yoga, or dietary supplements. * Epilepsy or any other concomitant neurological or neuromuscular disease affecting muscle tone, strength, or postural control that could interfere with the study. * Pharmacological treatment requiring frequent adjustments that would prevent treatment stability during the study. * Significant functional limitations, including balance problems, reduced mobility, inability to perform exercises on the floor, or inability to maintain prolonged positions, that prevent correct performance of the exercise protocol. * Insomnia unrelated to RLS. * Pregnancy or breastfeeding.