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Can skin scrapings reveal why ringworm beats antifungals?

NCT ID NCT07796854

Knowledge-focused Sponsor: Sohag University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 01, 2026 · Last updated Sep 02, 2026 · Updated 1 time

Summary

This study looks at adults with ringworm infections that resist standard antifungal treatment. Researchers will scrape the edge of the skin lesions and examine the samples under a microscope and in the lab to identify the fungus and test which antifungals might work. The goal is to understand the clinical, dermoscopic, and mycological features of these stubborn infections, which could guide better treatment choices.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Direct microscopic KOH examination and laboratory tests on skin scrapings
What this could lead to
If successful, this study could help doctors identify why some ringworm infections resist treatment and guide more effective antifungal choices.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test new therapies. Results may not apply to all patients or regions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

It's a cross sectional study will be conducted on patients attending the outpatient clinic of Dermatology, Venereology, and Andrology department in Sohag University Hospital over a period of 12 months between August, 2026 to July, 2027. Setting : Outpatient clinic of Dermatology, Venereology, and Andrology department in Sohag University Hospital.

Ages

1 year to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinically diagnosed resistant dermatophytosis (e.g., tinea corporis, cruris,…), resistant dermatophytosis (no cure despite adequate antifungals), recurrent (reoccurrence \<6 weeks post treatment) or disease duration \>6-12 months (Gharib et al., 2024) . 2. Age \>18 years, both sex. Exclusion Criteria: * Exclusion criteria 1. Pregnant or lactating women will be routinely excluded due to potential risks of antifungal medication. 2. Patients with recent systemic antifungal use (often within 1 month) or topical antifungals (within 2 weeks). 3. Chronic systemic diseases (e.g., diabetes mellitus, hepatic or renal impairment). 4. Patients receiving immunosuppressive drugs (systemic corticosteroids or other immunomodulatory drugs).

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Conditions

The condition(s) this trial relates to.

cutaneous mycosis dermatomycosis dermatophytosis Tinea tinea corporis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Fungal skin infection Tinea corporis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sohag university, Faculty of medicine

    Sohag, Egypt

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