Can weight training strengthen muscles in young CMT patients?
NCT ID NCT07152197
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at whether an 8-week supervised resistance exercise program can improve muscle quality, physical function, and quality of life in young people aged 15–29 with Charcot-Marie-Tooth disease (a type of hereditary nerve disorder). Participants will do lower-body exercises three times a week, with weights gradually increasing. The researchers will compare results between those with the condition and healthy volunteers to see if the exercise helps more in those with greater baseline weakness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Progressive resistance exercise training (supervised lower-limb exercises)
What this could lead to
If it works, this could show that resistance exercise is a safe, effective way to improve muscle function and quality of life in young people with Charcot-Marie-Tooth disease.
What could go wrong
This is a small, early-phase trial with only 22 participants, so results may not apply to everyone. The exercise program is short (8 weeks), and long-term benefits are unknown.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Temuco, Chile
RECRUITINGTemuco, La Araucanía, 4812790, Chile
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Universidad de La Frontera
ACTIVE_NOT_RECRUITINGTemuco, La Araucanía, 4812790, Chile