Study probes whether exercise and meditation shield aging brains from stress damage

NCT ID NCT05124132

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 468 older adults who previously took part in a trial of mindfulness and exercise. Researchers will measure how these lifestyle changes affect memory, emotional health, and biological markers of Alzheimer's risk. The goal is to understand how stress impacts the aging brain and whether sustained healthy habits can build resilience.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could reveal how lifestyle changes like mindfulness and exercise protect brain health and reduce Alzheimer risk in older adults.
What could go wrong: This is an observational follow-up, not a new treatment test. Results may not apply to all older adults, and the study cannot prove cause and effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGE-RELATED COGNITIVE DECLINE

Contacts and locations

Locations

Washington University School of Medicine

St Louis, Missouri, 63110, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.