Sitting less, moving more: new study reveals Body-Wide effects of activity changes

NCT ID NCT06377254

Recruiting now Knowledge-focused Sponsor: University of Nottingham Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how increasing or decreasing physical activity changes the way your body works. Forty overweight adults aged 50-65 will either become less active for 3 months then retrain, or become more active for 6 months. Researchers will measure fitness, muscle strength, brain function, and take tissue samples to understand the full-body impact.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could reveal how physical activity and inactivity impact multiple body systems, helping shape better public health advice for healthy aging.
What could go wrong: This is an early-stage observational intervention with only 40 participants. Results may not apply to everyone, and the study does not test a treatment or cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

abdominal obesity-metabolic syndrome metabolic syndrome X Motor Activity Overweight Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

David Greenfield Human Physiology Unit
RECRUITING

Nottingham, Notts, NG72UH, United Kingdom

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