New device automates fluid removal to ease heart failure symptoms

NCT ID NCT06272734

Recruiting now Symptom relief Sponsor: Reprieve Cardiovascular, Inc Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests the Reprieve System, a bedside device that automatically adjusts the delivery of a diuretic (furosemide) and saline based on the patient's real-time urine output. The goal is to safely and quickly remove excess fluid from 50 hospitalized adults with acute decompensated heart failure. The study focuses on whether the device works as intended without causing harm.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Reprieve System (a bedside device that automatically delivers the diuretic furosemide and saline based on real-time urine output)
What this could lead to: If successful, this device could offer a safer, more personalized way to remove excess fluid in heart failure patients, potentially reducing hospital stays and complications.
What could go wrong: This is a very early pilot study with only 50 participants, so results may not apply to all patients. The device could malfunction or cause side effects like dehydration or kidney issues.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

congestive heart failure heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE DECOMPENSATED HEART FAILURE

Contacts and locations

Locations

Tbilisi Heart and Vascular Clinic
RECRUITING

Tbilisi, 0159, Georgia

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