Nordic study aims to settle debate on best Clot-Busting approach for lung embolism

NCT ID NCT07003646

Recruiting now Knowledge-focused Sponsor: Sahlgrenska University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is tracking 220 adults across Nordic countries who receive either clot-dissolving drugs or a catheter-based procedure for a severe pulmonary embolism. Researchers are comparing how often each treatment leads to serious bleeding or death within 30 days. The goal is to provide real-world evidence on which approach is safer and more effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Alteplase
What this could lead to: If successful, this study could clarify which reperfusion method is safer and more effective for high-risk pulmonary embolism, guiding future treatment guidelines.
What could go wrong: This is an observational study, not a randomized trial, so results may be influenced by patient selection and cannot prove cause and effect. The small size (220 participants) limits generalizability.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULMONARY EMBOLISM

Contacts and locations

Locations

Aarhus University Hospital
RECRUITING

Aarhus, Denmark
Danderyd Hospital
RECRUITING

Stockholm, Sweden
Karolinska University Hospital Huddinge
RECRUITING

Stockholm, Sweden
Karolinska University Hospital Solna
RECRUITING

Stockholm, Sweden
Linköping University Hospital
RECRUITING

Linköping, Sweden
Odense University Hospital
RECRUITING

Odense, Denmark
Rigshospitalet
RECRUITING

Copenhagen, Denmark
Sahlgrenska University Hospital
RECRUITING

Gothenburg, 41345, Sweden
Skåne University Hospital
RECRUITING

Lund, Sweden
Sunderby Hospital
RECRUITING

Luleå, Sweden
Södersjukhuset
RECRUITING

Stockholm, Sweden
Uppsala University Hospital
NOT_YET_RECRUITING

Uppsala, Sweden
Örebro University Hospital
RECRUITING

Örebro, Sweden

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