Nordic study aims to settle debate on best Clot-Busting approach for lung embolism

NCT ID NCT07003646

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is tracking 220 adults across Nordic countries who receive either clot-dissolving drugs or a catheter-based procedure for a severe pulmonary embolism. Researchers are comparing how often each treatment leads to serious bleeding or death within 30 days. The goal is to provide real-world evidence on which approach is safer and more effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Alteplase

What this could lead to

If successful, this study could clarify which reperfusion method is safer and more effective for high-risk pulmonary embolism, guiding future treatment guidelines.

What could go wrong

This is an observational study, not a randomized trial, so results may be influenced by patient selection and cannot prove cause and effect. The small size (220 participants) limits generalizability.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulmonary embolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aarhus University Hospital

    RECRUITING

    Aarhus, Denmark

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Danderyd Hospital

    RECRUITING

    Stockholm, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

  • Karolinska University Hospital Huddinge

    RECRUITING

    Stockholm, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Karolinska University Hospital Solna

    RECRUITING

    Stockholm, Sweden

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Linköping University Hospital

    RECRUITING

    Linköping, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Odense University Hospital

    RECRUITING

    Odense, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Rigshospitalet

    RECRUITING

    Copenhagen, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sahlgrenska University Hospital

    RECRUITING

    Gothenburg, 41345, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact

  • Skåne University Hospital

    RECRUITING

    Lund, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Sunderby Hospital

    RECRUITING

    Luleå, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Södersjukhuset

    RECRUITING

    Stockholm, Sweden

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Uppsala University Hospital

    NOT_YET_RECRUITING

    Uppsala, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Örebro University Hospital

    RECRUITING

    Örebro, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact