Depression brain study withdrawn before it began

NCT ID NCT05991232

Terminated Knowledge-focused Sponsor: Jay Fournier Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to track brain activity in people with depression over time and see how a single dose of ketamine might change it. It was withdrawn before any participants were enrolled, so no results are available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Intravenous ketamine
What this could lead to: If successful, this could help identify brain targets for depression treatment and show how ketamine affects them.
What could go wrong: The study was withdrawn before enrolling anyone, so no data was collected. It was also small and early-stage, so results would have been preliminary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

depressive disorder endogenous depression major depressive disorder mood disorder psychiatric disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION, UNIPOLAR

Contacts and locations

Locations

The Ohio State University, Department of Psychiatry & Behavioral Health

Columbus, Ohio, 43210, United States

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