Depression brain study withdrawn before it began

NCT ID NCT05991232

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to track brain activity in people with depression over time and see how a single dose of ketamine might change it. It was withdrawn before any participants were enrolled, so no results are available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Intravenous ketamine

What this could lead to

If successful, this could help identify brain targets for depression treatment and show how ketamine affects them.

What could go wrong

The study was withdrawn before enrolling anyone, so no data was collected. It was also small and early-stage, so results would have been preliminary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

depressive disorder endogenous depression major depressive disorder mood disorder psychiatric disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Ohio State University, Department of Psychiatry & Behavioral Health

    Columbus, Ohio, 43210, United States