Brain stimulation study seeks clues to lasting depression relief
NCT ID NCT07684911
First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time
Summary
This study follows people with treatment-resistant depression who have already responded to transcranial magnetic stimulation (TMS). Researchers want to understand how long the antidepressant effect lasts and what factors—like brain plasticity, heart-brain coupling, or inflammation—might predict relapse. Participants receive standard TMS and are monitored with questionnaires, heart rate recordings, blood tests, and MRI scans. The goal is to find biomarkers that could guide personalized treatment plans.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- repetitive transcranial magnetic stimulation (rTMS)
- What this could lead to
- If successful, this could help doctors predict how long TMS benefits last and personalize treatment schedules to prevent relapse.
- What could go wrong
- This is a small observational study, not a treatment trial. It may not identify reliable predictors, and results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre Hospitalier Guillaume Régnier
RECRUITINGRennes, 35700, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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