Heart failure hope? kidney nerve procedure tested in tiny study

NCT ID NCT04947670

Terminated Disease control Sponsor: Universität des Saarlandes Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a procedure called renal denervation, which uses a catheter to calm overactive nerves in the kidneys, in people with chronic heart failure. The goal was to see if it is safe and feasible, and whether it could improve symptoms like walking distance and heart strain. Only 4 patients were enrolled before the study was terminated, so the results are very preliminary.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: renal denervation procedure
What this could lead to: If successful, this could point toward a new way to manage chronic heart failure by calming overactive nerves to the kidneys.
What could go wrong: This was a very small feasibility study (only 4 participants) that was terminated early, so results are limited. The procedure carries risks like any invasive vascular intervention.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardio-renal syndrome congestive heart failure heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIO-RENAL SYNDROME CHRONIC HEART FAILURE

Contacts and locations

Locations

Saarland University Medical Center, Department for Internal Medicine III

Homburg/Saar, Saarland, 66421, Germany

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