Could zapping kidney nerves tame stubborn high blood pressure and save hearts?
NCT ID NCT07602790
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a procedure called renal denervation, which uses a catheter to calm overactive nerves in the kidneys, in 1,000 people with both resistant hypertension and multivessel coronary artery disease. Participants will undergo the procedure during a planned heart stent operation and be followed for heart attacks, strokes, hospitalizations, and blood pressure changes. The goal is to see if this nerve treatment can reduce serious heart events better than standard blood pressure medications alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- renal denervation procedure
- What this could lead to
- If it works, this could offer a new way to control blood pressure and reduce heart attacks, strokes, and hospitalizations in people with both resistant hypertension and severe coronary artery disease.
- What could go wrong
- This is an early-stage study with no phase assigned, so results are uncertain. The procedure carries risks like kidney artery damage or contrast-related kidney injury, and it may not lower blood pressure enough to prevent heart events.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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