Online CBT shows promise for treating depression in rural communities

NCT ID NCT04120285

Completed Symptom relief Sponsor: University of South Florida Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving primary care doctors access to an online cognitive behavior therapy program helps treat major depression in rural West Virginia and Kentucky. Over 1,200 adults participated. The goal was to see if remote therapy can improve depression remission rates and be a practical option where mental health services are scarce.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: remote internet-based cognitive behavior therapy (eCBT)
What this could lead to: If successful, this could provide an effective, accessible treatment option for depression in rural areas with limited mental health resources.
What could go wrong: This is a completed study, but results may not apply to all populations. Online therapy may not work for everyone, and access to technology is required.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depression major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER

Contacts and locations

Locations

Harpers Ferry Family Medicine

Harpers Ferry, West Virginia, 25425, United States
Minnie Hamilton Health Systems

Glenville, West Virginia, 26351, United States
Minnie Hamilton Health Systems

Grantsville, West Virginia, 26147, United States
University of Lousiville Health

Louisville, Kentucky, 40202, United States
Upper Kanawha Clinic

Cedar Grove, West Virginia, 25039, United States
WVU Medicine

Morgantown, West Virginia, 26505, United States
Wayne Medical Clinic

Wayne, West Virginia, 25570, United States

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