Laser zaps recurrent brain tumors: new trial tests minimally invasive option
NCT ID NCT05124912
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is for people whose brain metastases have come back or caused radiation damage after initial treatment. It compares a laser-based procedure (LITT) plus standard care against standard care alone (steroids or repeat radiation). The goal is to see if LITT can better control tumor growth and help patients stop using steroids sooner. About 261 participants will be enrolled across multiple centers.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Laser Interstitial Thermal Therapy (LITT) using the NeuroBlate System
What this could lead to
If successful, this could offer a more effective, less invasive option to control recurrent brain tumors or radiation damage after initial treatment.
What could go wrong
This is a mid-stage trial with 261 participants, so results are not yet proven. Risks include surgical complications from LITT and the possibility that the treatment may not improve survival or reduce steroid use.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BRAIN METASTASES are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Email: •••••@•••••
Locations
-
Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
Contact Email: •••••@•••••
Contact
-
Duke University Hospital
ACTIVE_NOT_RECRUITINGDurham, North Carolina, 27710, United States
-
Kettering Health
RECRUITINGKettering, Ohio, 45429, United States
Contact
Contact Email: •••••@•••••
-
Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
-
UCLA
RECRUITINGLos Angeles, California, 90095, United States
Contact Email: •••••@•••••
Contact
-
University of Chicago
RECRUITINGChicago, Illinois, 60637, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
Contact
-
University of Maryland
RECRUITINGBaltimore, Maryland, 21201, United States
Contact
Contact Email: •••••@•••••
-
Wake Forest Baptist Medical Center
RECRUITINGWinston-Salem, North Carolina, 27157, United States
Contact
Contact Email: •••••@•••••
-
WashU
RECRUITINGSt Louis, Missouri, 63130, United States
Contact
Contact Email: •••••@•••••