Could a common numbing drug beat morphine for kidney stone pain?
NCT ID NCT07536594
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares lidocaine, a numbing drug, to morphine for treating severe kidney stone pain in the emergency room. Researchers will enroll 250 adults whose pain isn't relieved by standard treatment. The goal is to see if lidocaine provides better pain relief at 30 minutes, potentially offering a safer, non-opioid option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- lidocaine
- What this could lead to
- If lidocaine works better than morphine, it could offer a non-opioid option for kidney stone pain, helping to reduce opioid misuse.
- What could go wrong
- This is a small, early-stage trial with only 250 people. Previous promising results from Iran may not hold up in a more diverse U.S. population.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for KIDNEY STONES, UROLITHIASIS, HYPOCITRATURIA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- AI-Powered Ultra-Low radiation CT could revolutionize kidney stone diagnosis
- Massive study probes kidney stone risk for living donors
- New nerve block may ease kidney stone pain faster
- Could a steroid or asthma drug ease kidney stone pain?
- Why does kidney stone pain come back? new study tracks 878 patients
- Baking soda for kidney stones? new study tests cheaper alternative