Could a steroid or asthma drug ease kidney stone pain?

NCT ID NCT06980727

Not yet recruiting Symptom relief Sponsor: University of Monastir Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 16, 2026 · Updated 3 times

Summary

This study tests whether adding either dexamethasone (a steroid) or terbutaline (an asthma drug) to standard paracetamol provides better pain relief for people with kidney stones in the emergency room. About 300 adults with severe pain will be randomly assigned to one of the two drug combinations or a placebo. The main goal is to see if pain drops by at least half within a few hours.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexamethasone and terbutaline
What this could lead to: If it works, this could point toward a better, faster way to manage kidney stone pain in the emergency room.
What could go wrong: This is a single-center trial with 300 participants, so results may not apply to everyone. The drugs also have side effects like heart issues or infections.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Renal Colic urolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RENAL COLIC

Contacts and locations

Locations

University Hospital Fattouma Bourguiba Monastir

Monastir, Monastir Governorate, 5000, Tunisia

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