Can a mushroom ease breast cancer treatment side effects?
NCT ID NCT06028022
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether Reishi mushroom extract can reduce fatigue and joint pain in breast cancer patients taking aromatase inhibitors. About 80 women with moderate to severe fatigue will receive either the mushroom extract or a placebo for 8 weeks. The goal is to see if this natural supplement improves quality of life and helps patients stick with their cancer therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Reishi mushroom extract
What this could lead to
If it works, this could offer a natural option to ease fatigue and joint pain, helping patients stay on their cancer treatment longer.
What could go wrong
This is a small, early-phase trial. The extract may not work better than placebo, and side effects or interactions with cancer drugs are possible.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Locations
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Essentia Health Baxter Clinic
RECRUITINGBaxter, Minnesota, 56425, United States
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Essentia Health Cancer Center
RECRUITINGDuluth, Minnesota, 55805, United States
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Essentia Health Deer River Clinic
RECRUITINGDeer River, Minnesota, 56636, United States
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Essentia Health Ely Clinic
RECRUITINGEly, Minnesota, 55731, United States
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Essentia Health Fosston
RECRUITINGFosston, Minnesota, 56542, United States
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Essentia Health Hibbing Clinic
RECRUITINGHibbing, Minnesota, 55746, United States
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Essentia Health International Falls Clinic
RECRUITINGInternational Falls, Minnesota, 56649, United States
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Essentia Health Moose Lake
RECRUITINGMoose Lake, Minnesota, 55767, United States
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Essentia Health Park Rapids
RECRUITINGPark Rapids, Minnesota, 56470, United States
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Essentia Health Saint Joseph's Medical Center
RECRUITINGBrainerd, Minnesota, 56401, United States
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Essentia Health Saint Mary's - Detroit Lakes Clinic
RECRUITINGDetroit Lakes, Minnesota, 56501, United States
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Essentia Health Sandstone
RECRUITINGSandstone, Minnesota, 55072, United States
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Essentia Health Virginia Clinic
RECRUITINGVirginia, Minnesota, 55792, United States
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Fairview Grand Itasca Clinic & Hospital
RECRUITINGGrand Rapids, Minnesota, 55744, United States
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Fairview Northland Medical Center
RECRUITINGPrinceton, Minnesota, 55731, United States
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Fairview Range Medical Center
RECRUITINGHibbing, Minnesota, 55746, United States
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MMCORC CentraCare Monticello Cancer Center
COMPLETEDMonticello, Minnesota, 55362, United States
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Mayo Clinic Health System in Albert Lea
RECRUITINGAlbert Lea, Minnesota, 56007, United States
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Mayo Clinic Health Systems-Mankato
RECRUITINGMankato, Minnesota, 56001, United States
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Mayo Clinic in Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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Sanford Joe Lueken Cancer Center
RECRUITINGBemidji, Minnesota, 56601, United States
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Sanford Thief River Falls Medical Center
RECRUITINGThief River Falls, Minnesota, 56701, United States
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Sanford Worthington Medical Center
RECRUITINGWorthington, Minnesota, 56187, United States
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