Can targeted nerve blocks cut opioid use after pelvic fracture surgery?
NCT ID NCT07072286
First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time
Summary
This study tests whether adding regional anesthesia, such as nerve blocks, to standard pain treatment can reduce opioid use and pain after pelvic or acetabular fracture surgery. Adults undergoing surgery for these fractures may receive ultrasound-guided nerve blocks with a long-acting anesthetic, alongside the usual pain protocol. Researchers will track pain scores, opioid consumption, side effects, and recovery over 90 days to see if the blocks offer meaningful benefits.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Regional anesthesia nerve blocks (supra-inguinal fascia iliaca block, lumbar erector spinae plane block, transmuscular quadratus lumborum block) with ropivacaine, added to standard multimodal analgesia
- What this could lead to
- If it works, this could point toward a way to ease pain after pelvic fracture surgery while reducing reliance on opioids and their side effects.
- What could go wrong
- This is a small pilot study, so results may not apply broadly. Nerve blocks carry risks like bleeding, infection, or anesthetic allergy, and the benefit over standard care is not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 177 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2024
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with pelvic/acetabular fractures presenting to the Emergency and Trauma Department, either as primary transport or secondary referral, who require surgery (percutaneous or via open reduction/internal fixation).
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years and ability to provide informed consent * Patients with pelvic/acetabular fractures requiring surgery Exclusion Criteria * Age \< 18 years * Absolute contraindications to ALR techniques (uncorrectable coagulopathies, known allergy to local anesthetics, technical impossibility of execution)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centro Traumatologico Ortopedico (CTO) - AOU Città della Salute e della Scienza Univeristy Hospital
RECRUITINGTurin, 10126, Italy
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