Nerve implants could give amputees better control of robotic legs

NCT ID NCT06275282

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tests whether small implants placed on nerves in the thigh can help people with above-knee amputations control a robotic leg more naturally and feel sensations from it. Three participants will undergo surgery to create regenerative nerve interfaces and have electrodes implanted. Over a year, researchers will measure signal strength, movement accuracy, and sensory feedback. The goal is to improve function and quality of life, but the trial is very small and the electrodes are removed after the study.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

regenerative peripheral nerve interfaces (RPNIs) with implanted electrodes

What this could lead to

If it works, this could lead to better control and natural feeling of advanced prosthetic legs for people with above-knee amputations.

What could go wrong

This is a very early, tiny trial with only 3 participants. The surgery is invasive, and the electrodes are removed after one year. It may not work for everyone or lead to a long-term solution.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact