Could skipping radiation be just as effective for rectal cancer?

NCT ID NCT03875781

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using chemotherapy alone before surgery works as well as chemotherapy followed by radiation for people with locally advanced rectal cancer. About 540 adults with stage T3 or node-positive rectal cancer will take part. The goal is to see if avoiding radiation can maintain cancer control while reducing side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • BENOIST

    RECRUITING

    Le Kremlin-Bicêtre, Île-de-France Region, 94275, France

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