New trial aims to save rectums in rectal cancer patients

NCT ID NCT06952101

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a personalized, stage-based approach to treat rectal cancer while trying to avoid removing the rectum. 200 participants will receive either experimental chemoradiotherapy or minimally invasive surgery depending on their cancer stage. The goal is to preserve the rectum and improve quality of life without compromising cancer control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

chemoradiotherapy (experimental and standard), minimally invasive surgery (laparoscopic/robotic)

What this could lead to

If successful, this could offer a way to treat rectal cancer without removing the rectum, preserving bowel function and quality of life for many patients.

What could go wrong

This is an early-phase study with only 200 participants, so results may not apply to everyone. The organ-sparing approach may not work for all patients, and some may still need surgery or face cancer recurrence.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Department of Surgical Oncology - FPO-IRCCS Institute for Cancer Research and Treatment

    RECRUITING

    Candiolo, Turin, 10060, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact