New nerve treatment could ease heart failure symptoms

NCT ID NCT04592445

Recruiting now Disease control Sponsor: Axon Therapies, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a procedure that uses a catheter to treat a nerve in the body, aiming to improve symptoms in people with a type of heart failure called HFpEF. About 150 participants will be enrolled to see if the procedure is safe and effective. The goal is to help patients feel better and identify who might benefit most from this treatment.

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Conditions

The condition(s) this trial relates to.

diastolic heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFPEF)

Contacts and locations

Locations

Arizona Cardiovascular Research Center
ACTIVE_NOT_RECRUITING

Phoenix, Arizona, 85016, United States
Ascension St. Vincent - Cardiovascular Research Institute
COMPLETED

Indianapolis, Indiana, 46260, United States
Bluhm Cardiovascular Institute of Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States
Cardiology PC
COMPLETED

Birmingham, Alabama, 35211, United States
Cardiovascular Institute of the South
RECRUITING

Houma, Louisiana, 70360, United States
Columbia University Medical Center
RECRUITING

New York, New York, 10032, United States
Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States
Icahn School of Medicine at Mount Sinai
ACTIVE_NOT_RECRUITING

New York, New York, 10029, United States
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Medical University of South Carolina
RECRUITING

Charleston, South Carolina, 29425, United States
Michigan Medicine, University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States
Ohio State University Wexner Medical Center
RECRUITING

Columbus, Ohio, 43210, United States
Prairie Education and Research Cooperative
ACTIVE_NOT_RECRUITING

Springfield, Illinois, 62701, United States
Rochester General Hospital
RECRUITING

Rochester, New York, 14621, United States
Scripps Health
ACTIVE_NOT_RECRUITING

La Jolla, California, 92037, United States
St. Louis Heart and Vascular
RECRUITING

St Louis, Missouri, 63136, United States
University of California, San Francisco
RECRUITING

San Francisco, California, 94143, United States
University of Chicago Medical Center
RECRUITING

Chicago, Illinois, 60637, United States
Virginia Commonwealth University Medical Center
ACTIVE_NOT_RECRUITING

Richmond, Virginia, 23298, United States
Weill Cornell Medicine
RECRUITING

New York, New York, 10021, United States

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