New drug hopes to stop relapses in kids with rare nerve disease
NCT ID NCT05346354
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests ravulizumab, a drug that calms a part of the immune system, in 12 children with NMOSD – a rare disease where the immune system attacks the nerves in the eyes and spine. The goal is to see if the drug can reduce the number of relapses and prevent disability over about a year. All children receive the drug; there is no placebo group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ravulizumab (Ultomiris) – a drug that blocks part of the immune system to prevent attacks
What this could lead to
If it works, this could offer a treatment option for children with NMOSD to reduce relapses and slow disability.
What could go wrong
This is a small, early-phase trial with only 12 participants and no placebo group, so results may not apply broadly. The drug also increases risk of serious infections.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Research Site
Washington D.C., District of Columbia, 20010, United States
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Research Site
Miami, Florida, 33136, United States
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Research Site
Boston, Massachusetts, 02114, United States
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Research Site
Durham, North Carolina, 27705, United States
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Research Site
Philadelphia, Pennsylvania, 19104, United States
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Research Site
Edmonton, Alberta, T6G 1C9, Canada
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Research Site
Toronto, Ontario, M5G 1X8, Canada
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Research Site
Montreal, Quebec, H3T1C5, Canada
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Research Site
Le Kremlin-Bicêtre, 94270, France
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Research Site
Marseille, 13005, France
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Research Site
Chieti, 66013, Italy
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Research Site
Gallarate, 21013, Italy
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Research Site
Roma, 00165, Italy
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Research Site
Yokohama, 232-0024, Japan
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Research Site
Goyang-si, 10408, South Korea
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Research Site
Esplugues de Llobregat, 8950, Spain