New hope for rare cancers: drug combo trial launches

NCT ID NCT04449549

First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 29 times

Summary

This study tests two drugs, nilotinib and paclitaxel, together in people with rare advanced cancers that have not responded to standard treatments. The goal is to see if the combination can shrink or stop tumor growth. About 82 adults with specific rare cancers like certain ovarian cancers, anal cancer, or Ewing sarcoma will take part. Participants take nilotinib by mouth twice daily and receive paclitaxel through a vein once a week for three weeks of each 28-day cycle.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NEOPLASMS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.