Heart attack drug aims to save tiny vessels

NCT ID NCT07380919

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether the drug ranolazine can protect the tiny blood vessels in the heart after a heart attack. One hundred adults who had a major heart attack and have at least one other blocked artery will receive either ranolazine plus standard care or standard care alone. The main goal is to see if ranolazine helps keep the small vessels working better, measured by a special index at the start and after about six weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ranolazine

What this could lead to

If it works, this could point toward a new way to protect the heart's tiny blood vessels after a heart attack, potentially reducing long-term damage.

What could go wrong

This is a mid-stage trial with only 100 participants, so results may not apply to everyone. Ranolazine can cause side effects like dizziness, nausea, and constipation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Cardiology, Santa Maria Goretti Hospital, Latina, Italy

    NOT_YET_RECRUITING

    Latina, Italy, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Medical and Surgical Sciences and "Renato Dulbecco" University Hospital, "Magna Graecia" University

    RECRUITING

    Catanzaro, Italy, 88100, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Federico II University Hospital - Division of Cardiology

    RECRUITING

    Naples, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••