New test may predict which breast cancer patients benefit from targeted drug
NCT ID NCT05340413
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a test called RAD51-foci can predict how well the drug olaparib works in people with advanced HER2-negative breast cancer who have certain gene mutations (BRCA1, BRCA2, PALB2, RAD51C, or RAD51D). About 65 participants received olaparib, and researchers measured tumor response. The goal is to better match patients to effective treatment and avoid unnecessary side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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H Clinic de Barcelona
Barcelona, Spain
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H Vall d Hebron
Barcelona, Spain
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H. 12 de Octubre
Madrid, Spain
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H. C. U. Valencia
Valencia, Spain
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H. San Cecilio
Granada, Spain