New test may predict who benefits from targeted breast cancer drug

NCT ID NCT05340413

First seen Mar 16, 2026 · Last updated May 15, 2026 · Updated 8 times

Summary

This study tested a new lab test (RAD51-foci) to see if it can predict whether the drug olaparib will shrink tumors in people with advanced HER2-negative breast cancer who have certain gene mutations (BRCA1, BRCA2, PALB2, RAD51C, or RAD51D). The study involved 65 participants and aimed to improve how doctors choose treatments. The main goal was to see if the test could tell which patients would respond best to olaparib.

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Contacts and locations

Locations

  • H Clinic de Barcelona

    Barcelona, Spain

  • H Vall d Hebron

    Barcelona, Spain

  • H. 12 de Octubre

    Madrid, Spain

  • H. C. U. Valencia

    Valencia, Spain

  • H. San Cecilio

    Granada, Spain

Conditions

Explore the condition pages connected to this study.