Can heat zap lung tumors without surgery?

NCT ID NCT00180856

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This trial tests whether radiofrequency ablation—a procedure that uses heat to destroy cancer cells—can effectively treat lung tumors that cannot be removed with surgery. The study includes people with primary lung cancer or lung metastases, with up to five tumors each no larger than 40 mm. Researchers will measure how completely the tumors are destroyed, how long patients live without lung disease progression, and overall survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Radiofrequency ablation, a procedure that uses heat to destroy tumor cells
What this could lead to
If successful, this could offer a treatment option for people with lung tumors that cannot be surgically removed, potentially improving local control and survival.
What could go wrong
This is a phase II trial with a modest number of participants, so results may not be definitive. The procedure may not completely destroy all tumors, and there are risks of complications from the ablation itself.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LUNG CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Institut Bergonié

    Bordeaux, 33 000, France

  • Institut Gustave Roussy

    Villejuif, 94800, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.