Radiation after failed CAR t: tiny study halted early
NCT ID NCT04473937
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This pilot study looked at whether radiation therapy could help people with lymphoma that did not respond to CAR T cell therapy. Only 3 participants were enrolled before the study was terminated. The main goal was to check safety and side effects of adding radiation shortly after CAR T treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Radiotherapy
- What this could lead to
- If it works, this could offer a way to improve outcomes for lymphoma patients who don't respond to CAR T cell therapy.
- What could go wrong
- This was a very small pilot study (only 3 participants) that was terminated early, so we have very little data. The approach may not be effective or safe for most patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114, United States
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