New combo therapy targets Hard-to-Treat bile duct cancer

NCT ID NCT04708067

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 34 times

Summary

This early-phase trial tests a new approach for people with advanced bile duct cancer that has spread. It combines a special type of radiation (given in fewer, stronger doses) with an immunotherapy drug called bintrafusp alfa, which helps the immune system fight cancer. The goal is to find the safest dose and see if the combination can shrink tumors or slow the disease. Only 2 participants were enrolled, so results are very preliminary.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.