New combo therapy targets Hard-to-Treat bile duct cancer

NCT ID NCT04708067

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 25 times

Summary

This early-phase trial tests a new treatment for advanced bile duct cancer that has spread. It combines a special type of radiation (given in fewer, stronger doses) with an immunotherapy drug called bintrafusp alfa, which helps the immune system fight cancer. The study includes about 2 adults who have already tried standard chemotherapy. The main goal is to find the safest dose and see if the combination can shrink tumors or slow their growth.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.