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New portable brain scanner could ease Alzheimer's imaging bottleneck

NCT ID NCT06757569

Recruiting now Diagnosis Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new, smaller and mobile PET scanner called the Radialis PET Imager (RPI) to see if it can produce brain images as good as standard PET scanners for detecting amyloid plaques—a hallmark of Alzheimer's disease. Researchers will enroll 160 adults with cognitive impairment who are already scheduled for a standard amyloid PET scan. Participants will get an extra scan on the RPI device. The goal is to see if the RPI can provide comparable images, which could make amyloid imaging more widely available and affordable.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Radialis PET Imager (device) with 18F-Florbetaben tracer
What this could lead to
If successful, this could provide a cheaper, more portable alternative for brain amyloid PET scans, helping meet the growing demand for Alzheimer's imaging.
What could go wrong
This is an early feasibility study (not yet approved by Health Canada) and only compares image quality to standard scanners. It does not test treatment or outcomes, and the device may not prove equivalent in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Alzheimer disease Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COGNITIVE IMPAIRMENT

Contacts and locations

Locations

  • University Health Network, Toronto

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

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