New antibody cocktail aims to stop rabies after multiple dog bites
NCT ID NCT07624461
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a new antibody injection, called zamerovimab and mazorelvimab, combined with the standard rabies vaccine, can prevent rabies in people who have been severely bitten by a dog. The trial follows 80 adults in China for up to one year to see if they stay rabies-free. The goal is to improve protection after high-risk exposures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- zamerovimab and mazorelvimab injection (a human rabies antibody cocktail) plus rabies vaccine
- What this could lead to
- If successful, this could offer a more effective way to prevent rabies after severe dog bites, potentially saving lives in areas where rabies is common.
- What could go wrong
- This is a small, early real-world study with only 80 participants, so results may not apply to everyone. The treatment might not prevent rabies in all cases, and side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The Disease Prevention and Control Center of Nanyang
Nanyang, Henan, 473000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Experimental antibody cocktail offers hope for rabies patients with no other options
- New vaccines for yellow fever and rabies enter first human tests
- New rabies vaccine shows promise in large trial
- New rabies antibody shot tested in kids – could replace current treatment?
- Could a tiny skin shot replace the big rabies needle?
- New rabies shot shows promise in preventing deadly infection after bites