New vaccines for yellow fever and rabies enter first human tests
NCT ID NCT06998004
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tested two new vaccines—one for yellow fever and one for rabies—in 112 healthy adults aged 18 to 40. The main goal was to check safety and see how well the vaccines trigger an immune response. Participants received different doses or a placebo to help find the best balance of safety and effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- AVX70120 (yellow fever vaccine) and AVX70481 (rabies vaccine)
- What this could lead to
- If successful, these vaccines could provide new options to prevent yellow fever and rabies, potentially improving protection for travelers and people in affected regions.
- What could go wrong
- This is a very early Phase 1 trial with only 112 healthy adults. The vaccines may not trigger a strong enough immune response or could have unexpected side effects. Much more testing is needed before they could be widely used.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for RABIES are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Centre for the Evaluation of Vaccination (CEV)
Antwerp, Belgium
-
University Hospital Ghent - Centrum voor Vaccinologie (CEVAC)
Ghent, Belgium
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Experimental antibody cocktail offers hope for rabies patients with no other options
- New antibody cocktail aims to stop rabies after multiple dog bites
- New yellow fever vaccine shows promise in Mid-Stage trial
- New yellow fever vaccine shows promise in early human trial
- New rabies vaccine shows promise in large trial
- 10,000 people tested: Cambodia's massive disease hunt begins