Experimental antibody cocktail offers hope for rabies patients with no other options
NCT ID NCT07706907
First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time
Summary
This program provides access to SYN023, a combination of two lab-made antibodies (zamerovimab and mazorelvimab) designed to neutralize the rabies virus. It is for people in the United States with confirmed or suspected life-threatening rabies who cannot join other studies or access approved treatments. The antibodies are given alongside standard rabies care, and the goal is to offer a potential treatment when no alternatives exist.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a dual monoclonal antibody cocktail (zamerovimab and mazorelvimab) targeting the rabies virus
- What this could lead to
- If effective, this could provide a new treatment option for people with life-threatening rabies, a disease that is almost always fatal once symptoms appear.
- What could go wrong
- This is an expanded access program, not a formal trial, so evidence of benefit is limited. Rabies is extremely difficult to treat, and the antibodies may not change the outcome.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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