New rabies shot shows promise in preventing deadly infection after bites

NCT ID NCT03961555

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study tested a new medicine called SYN023 to prevent rabies in people who were bitten or scratched by animals like dogs or bats. About 448 adults with different levels of rabies risk received either SYN023 or the standard rabies immune globulin, along with the rabies vaccine. The goal was to see if SYN023 works as well as the current treatment to stop rabies from developing.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asian Hospital and Medical Center

    Muntinlupa, National Capital Region, 1780, Philippines

  • Baguio General Hospital and Medical Center

    Baguio City, Benguet, 2600, Philippines

  • Center of Excellence in Drug Research, Evaluation and Studies, Inc.

    Muntinlupa, National Capital Region, 1781, Philippines

  • Clinical Research Solutions PC -Milan

    Milan, Tennessee, 38358, United States

  • De La Salle Health Sciences Institute Independent Ethics Committee

    Cavite City, Calabarzon, 4114, Philippines

  • Far Eastern University Hospital Nicanor Reyes Medical Foundation

    Quezon City, National Capital Region, 1118, Philippines

  • Manila Doctors Hospital Institutional Review Board

    Manila, National Capital Region, 1000, Philippines

  • Mary Johnston Hospital

    Manila, Philippines

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Research Institute For Tropical Medicine

    Muntinlupa, National Capital Region, 1781, Philippines

  • Southern Philippines Medical Center

    Davao City, Davao (Region XI), 8000, Philippines

  • University of Florida

    Gainesville, Florida, 32610, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Virginia

    Charlottesville, Virginia, 22903, United States

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