New rabies shot shows promise in preventing deadly infection after bites
NCT ID NCT03961555
First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times
Summary
This study tested a new medicine called SYN023 to prevent rabies in people who were bitten or scratched by animals like dogs or bats. About 448 adults with different levels of rabies risk received either SYN023 or the standard rabies immune globulin, along with the rabies vaccine. The goal was to see if SYN023 works as well as the current treatment to stop rabies from developing.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Asian Hospital and Medical Center
Muntinlupa, National Capital Region, 1780, Philippines
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Baguio General Hospital and Medical Center
Baguio City, Benguet, 2600, Philippines
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Center of Excellence in Drug Research, Evaluation and Studies, Inc.
Muntinlupa, National Capital Region, 1781, Philippines
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Clinical Research Solutions PC -Milan
Milan, Tennessee, 38358, United States
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De La Salle Health Sciences Institute Independent Ethics Committee
Cavite City, Calabarzon, 4114, Philippines
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Far Eastern University Hospital Nicanor Reyes Medical Foundation
Quezon City, National Capital Region, 1118, Philippines
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Manila Doctors Hospital Institutional Review Board
Manila, National Capital Region, 1000, Philippines
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Mary Johnston Hospital
Manila, Philippines
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Research Institute For Tropical Medicine
Muntinlupa, National Capital Region, 1781, Philippines
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Southern Philippines Medical Center
Davao City, Davao (Region XI), 8000, Philippines
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University of Florida
Gainesville, Florida, 32610, United States
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University of Iowa
Iowa City, Iowa, 52242, United States
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University of Virginia
Charlottesville, Virginia, 22903, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Experimental antibody cocktail offers hope for rabies patients with no other options
- New antibody cocktail aims to stop rabies after multiple dog bites
- New vaccines for yellow fever and rabies enter first human tests
- New rabies vaccine shows promise in large trial
- Could a tiny skin shot replace the big rabies needle?
- New rabies vaccine passes first safety check in small trial