New rabies antibody shot tested in kids – could replace current treatment?
NCT ID NCT07342257
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new combination of lab-made antibodies (SYN023) given alongside the rabies vaccine to healthy children under 18. The goal was to see if it is safe and how well it works compared to the standard treatment. A total of 108 children received either a low or high dose of SYN023 or the usual rabies immune globulin, plus the vaccine over 28 days. The trial is now complete, and results will help decide if larger studies are warranted.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Zamerovimab and Mazorelvimab injection (SYN023), a combination of two lab-made antibodies
What this could lead to
If successful, this could provide a safer or more effective option for preventing rabies after an animal bite in children.
What could go wrong
This is an early Phase 1 trial with only 108 participants, so safety and effectiveness are not yet proven. The results may not apply to all children or real-world bite scenarios.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Yuping Dong Autonomous County Center for Disease Control and Prevention
Tongren, Guizhou, 554000, China