Could a swab or a cough sound diagnose TB in kids?
NCT ID NCT05989802
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing new, non-invasive ways to diagnose tuberculosis (TB) in children under 15. Researchers will evaluate oral swabs, cough sound analysis, and lung sound analysis as potential alternatives to sputum tests. The goal is to find faster, simpler, and cheaper diagnostic tools to help reduce the 230,000 childhood TB deaths that occur each year. The study will enroll about 2,100 children at clinics in high-burden settings.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Oral swab molecular testing, automated cough sound analysis, automated lung sound analysis
What this could lead to
If successful, these tests could provide faster, simpler, and cheaper ways to diagnose TB in children, potentially saving many young lives.
What could go wrong
This is a diagnostic accuracy study, not a treatment trial. The new tests may not be accurate enough to replace current methods, and results may not apply to all settings.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dora Nginza Hospital
NOT_YET_RECRUITINGCape Town, South Africa
Contact Email: •••••@•••••
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Instituto Nacional de Saúde
RECRUITINGMaputo, Mozambique
Contact Email: •••••@•••••
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Mulago National Referral Hospital
NOT_YET_RECRUITINGKampala, Uganda
Contact Email: •••••@•••••