New study aims to understand how ascites affects daily life and muscle health

NCT ID NCT05726747

Recruiting now Knowledge-focused Sponsor: Abramson Cancer Center at Penn Medicine Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 70 adults with refractory ascites (fluid buildup in the belly that doesn't respond to standard treatment) caused by liver disease or cancer. Researchers will use surveys to measure quality of life and CT scans to track muscle loss (sarcopenia) over time. The goal is to better understand how these conditions change, which could lead to future treatments to help patients feel better and stay stronger.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help design future treatments to improve quality of life and prevent muscle wasting in patients with refractory ascites.
What could go wrong: This is an observational study with only 70 participants, so results may not apply to everyone. It does not test any treatment directly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Ascites cirrhosis of liver Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASCITES HEPATIC ASCITES, MALIGNANT

Contacts and locations

Locations

University of Pennsylvania Perelman School of Medicine
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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