Should surgeons add a pyloric drainage step during esophagectomy? new trial aims to find out.
NCT ID NCT03740542
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two surgical approaches for people having their esophagus removed (esophagectomy): one group gets the standard surgery plus an extra drainage procedure on the stomach (pyloroplasty), and the other gets the standard surgery alone. The goal is to see if the extra step reduces serious complications like pneumonia and leaks where the esophagus is reconnected. About 143 adults aged 18–85 are taking part.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- pyloroplasty (a surgical drainage procedure on the pylorus)
- What this could lead to
- If successful, this could show that adding pyloroplasty during esophagectomy reduces complications like pneumonia and leaks, improving recovery.
- What could go wrong
- This is a relatively small, single-center surgical trial. The benefit may be small or not apply to all patients, and surgery always carries risks like infection or bleeding.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Department of Cardiothoracic Surgery
Pittsburgh, Pennsylvania, 15232, United States
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University of Pittsburgh Medical Center Presbyterian-Shadyside Hospital
Pittsburgh, Pennsylvania, 15213, United States
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