Could pine bark ease gulf war symptoms? small trial aims to find out
NCT ID NCT07266571
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will test whether Pycnogenol, a supplement from French maritime pine bark, can reduce symptoms of Gulf War Illness like fatigue, pain, and brain fog. Twenty male veterans who have already been in a related study will take either Pycnogenol or a placebo for up to 12 months. The goal is to see if it improves physical and mental functioning and to find the best dose.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Pycnogenol (French maritime pine bark extract)
- What this could lead to
- If it works, this could point toward a natural supplement to reduce inflammation and improve daily functioning for veterans with Gulf War Illness.
- What could go wrong
- This is a very small, early-stage trial with only 20 male veterans, so results may not apply to everyone. As a dietary supplement, it is not FDA-approved as a drug, and its effects may be modest or no better than placebo.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Alabama at Birmingham
Birmingham, Alabama, 35243, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.