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Eye test could unlock secrets of night owl disorder

NCT ID NCT06949644

Recruiting now Knowledge-focused Sponsor: Northwestern University Source: ClinicalTrials.gov ↗

First seen Apr 10, 2026 · Last updated May 25, 2026 · Updated 10 times

Summary

This study looks at how the pupils of people with delayed sleep-wake phase disorder react to light. Researchers want to see if there are differences in light sensitivity and whether a single dose of citalopram can boost melatonin suppression during bright light exposure. About 220 adults with the disorder will do sleep and melatonin tests at home, then an eye exam. A smaller group will also stay overnight twice to have their melatonin measured before and after light, once with a placebo and once with citalopram.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

DELAYED SLEEP-WAKE PHASE DISORDER