Tooth decay clues: scientists measure inflammation markers to improve Kids' dental care
NCT ID NCT07171229
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at 58 children with deep cavities in their baby molars. Dentists will perform a pulpotomy (removing the infected nerve and sealing the tooth) and measure levels of cytokines—substances that signal inflammation—in the pulp. The goal is to see if these levels can predict whether the treatment succeeds, based on pain, infection, and healing over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Pulpotomy (a dental procedure to remove infected pulp, using MTA as a medicament)
- What this could lead to
- If successful, this could help dentists better predict which baby teeth with decay will respond well to pulpotomy, reducing the need for extractions.
- What could go wrong
- This is a small, early-stage study (58 children) that only measures short-term outcomes. It may not prove that cytokine levels reliably predict success, and results may not apply to all children.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cairo Univeristy
Cairo, Egypt
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Other studies related to the condition(s) this trial covers.
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