Tooth decay clues: scientists measure inflammation markers to improve Kids' dental care

NCT ID NCT07171229

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at 58 children with deep cavities in their baby molars. Dentists will perform a pulpotomy (removing the infected nerve and sealing the tooth) and measure levels of cytokines—substances that signal inflammation—in the pulp. The goal is to see if these levels can predict whether the treatment succeeds, based on pain, infection, and healing over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pulpotomy (a dental procedure to remove infected pulp, using MTA as a medicament)

What this could lead to

If successful, this could help dentists better predict which baby teeth with decay will respond well to pulpotomy, reducing the need for extractions.

What could go wrong

This is a small, early-stage study (58 children) that only measures short-term outcomes. It may not prove that cytokine levels reliably predict success, and results may not apply to all children.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dental caries pit and fissure surface dental caries pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cairo Univeristy

    Cairo, Egypt

    Contact Phone: •••-•••-••••