Glow-in-the-Dark probe could save parathyroid glands during thyroid surgery
NCT ID NCT06765941
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether a device called PTeye, which uses near-infrared light to make parathyroid glands glow, helps surgeons find and protect these tiny glands during thyroid surgery. The trial will compare outcomes in 154 patients who have their first total thyroidectomy, with half using PTeye and half relying on the surgeon's naked eyes. The goal is to see if PTeye reduces accidental removal of parathyroids and lowers the risk of postoperative hypoparathyroidism, a condition that can require lifelong calcium and vitamin D supplements.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- PTeye (probe-based near-infrared parathyroid autofluorescence detection system)
- What this could lead to
- If successful, this device could help surgeons better identify and preserve parathyroid glands during thyroid surgery, reducing the risk of permanent calcium and vitamin D dependency.
- What could go wrong
- This is a relatively small trial (154 participants) testing a device against standard practice. The benefit may be modest, and the device may not work for all patients or in all surgical settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Endocrine Surgery, Faculty of Medicine, Jagiellonian University Medical College
RECRUITINGKrakow, Małopolska, 31-501, Poland
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Other studies related to the condition(s) this trial covers.
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